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In
U.S. whites, 78.5% of group A
individuals belongs to subgroup
A1 and almost all of the remainders
are A2. about one in 1,000 group
A blood belongs to subgroup A3.
The frequency of Ax in France
is estimated as one in 77,000.
In the yellow race, remarkably
fewer subgroup A2, A3 and Ax are
reported. It is found that only
three B3 in 350,000 French donors.
 Subgroup
B3 is much higher in the yellow
race. For example, in Chinese,
one in 900 group B donors is B3
and one in 1,800 A1B donors is
A1B3. In Japan, Yamaguchi et al.
studied more than 700,000 donors
and found that the frequencies
of Bx are considerably higer than
of Ax. Therefore, it is more important
to detect the group B blood in
yellow race than in Caucasian.
The anti-A blood grouping reagent
has the agglutination ability
equivalent to most other commercial
test kits. In contrast the anti-B
blood grouping reagent has the
ability to detect most of the
weak subgroups of the B antigens,
such as B3, AB3, Bx and ABx. Therefore,
the ABO blood grouping reagent
is more specific and suitable
for oriental-blood typing.
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Features
different from other commercial
blood grouping reagents:
1.The hybridomas producing the
anti-A and anti-B monoclonal antibodies
are developed in Taiwan.
2.The anti-B blood grouping reagent
has stronger agglutination titer
to detect most of the weak subgroups
of the B antigens.
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